Anti-SAP49 Antibody
Our Anti-SAP49 primary antibody from PhosphoSolutions is mouse monoclonal. It detects human, mouse,
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
---|---|
Primary Accession | Q15427 |
Reactivity | Bovine |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG2b |
Clone Names | 3A1 |
Calculated MW | 44386 Da |
Gene ID | 10262 |
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Other Names | AFD1 antibody, Hsh49 antibody, MGC10828 antibody, Pre mRNA splicing factor SF3b 49 kDa subunit antibody, Pre-mRNA-splicing factor SF3b 49 kDa subunit antibody, SAP 49 antibody, SAP49 antibody, Sf3b4 antibody, SF3B4 antibody, SF3B4_HUMAN antibody, SF3b49 antibody, SF3b50 antibody, Spliceosomal protein antibody, Spliceosome associated protein (U2 snRNP) antibody, Spliceosome associated protein 49 antibody, Spliceosome-associated protein 49 antibody, Splicing factor 3b subunit 4 49kDa antibody, Splicing factor 3B subunit 4 antibody |
Target/Specificity | The spliceosome associated protein of ~49 kDa (SAP49), also known as SF3B4, is a widely expressed nuclear splicing factor that has been shown to have RNA binding activity as well as direct interaction with SAP145 (Champion-Arnaud and Reed 1994). The SAP145-SAP49 complex has recently been implicated in cell cycle progression as Vpr (viral protein 1 of HIV-1) has been shown to bind SAP145 thus interfering with the proper formation and functioning of the SAP145-SAP49 complex (Terada and Yasuda 2006). |
Format | Protein G Purified |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Anti-SAP49 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Shipping | Blue Ice |
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Provided below are standard protocols that you may find useful for product applications.
Background
The spliceosome associated protein of ~49 kDa (SAP49), also known as SF3B4, is a widely expressed nuclear splicing factor that has been shown to have RNA binding activity as well as direct interaction with SAP145 (Champion-Arnaud and Reed 1994). The SAP145-SAP49 complex has recently been implicated in cell cycle progression as Vpr (viral protein 1 of HIV-1) has been shown to bind SAP145 thus interfering with the proper formation and functioning of the SAP145-SAP49 complex (Terada and Yasuda 2006).
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