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Anti-NG2/CSPG4 Antibody
Our NG2/CSPG4 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It dete
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- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q6UVK1 |
| Reactivity | Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 250537 Da |
| Gene ID | 1464 |
|---|---|
| Other Names | 4732461B14Rik antibody, AN2 antibody, AN2 proteoglycan antibody, Chondroitin sulfate proteoglycan 4 (melanoma-associated) antibody, Chondroitin sulfate proteoglycan 4 antibody, Chondroitin sulfate proteoglycan NG2 antibody, Cspg4 antibody, Cspg4 chondroitin sulfate proteoglycan 4 antibody, CSPG4_HUMAN antibody, HMW-MAA antibody, HSN tumor-specific antigen antibody, Kiaa4232 antibody, MCSP antibody, MCSPG antibody, MEL-CSPG antibody, Melanoma chondroitin sulfate proteoglycan antibody, Melanoma-associated chondroitin sulfate proteoglycan antibody, MELCSPG antibody, MSK16 antibody, NG2 antibody |
| Target/Specificity | Neuron-glial antigen 2 (NG2) is a chondroitin sulfate proteoglycan that is encoded by the CSPG4 gene in humans. It is an excellent oligodendrocyte marker. NG2 is a hallmark protein of oligodendrocyte progenitor cells (OPCs) and has been linked with familial schizophrenia (de Vrij, F.M., et al, 2018). NG2 also plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. It represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells (Luo, W., et al, 2006). NG2 localizes at the apical plasma membrane and relocalizes to the lamellipodia of astrocytoma upon PRKCA phosphorylation. |
| Format | Antigen Affinity Purified from Pooled Serum |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Anti-NG2/CSPG4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Shipping | Blue Ice |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Neuron-glial antigen 2 (NG2) is a chondroitin sulfate proteoglycan that is encoded by the CSPG4 gene in humans. It is an excellent oligodendrocyte marker. NG2 is a hallmark protein of oligodendrocyte progenitor cells (OPCs) and has been linked with familial schizophrenia (de Vrij, F.M., et al, 2018). NG2 also plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. It represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells (Luo, W., et al, 2006). NG2 localizes at the apical plasma membrane and relocalizes to the lamellipodia of astrocytoma upon PRKCA phosphorylation.
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