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PNOC Antibody (Center)
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q13519 |
| Reactivity | Human |
| Predicted | Human |
| Host | Mouse |
| Clonality | monoclonal |
| Isotype | IgG2b,κ |
| Clone/Animal Names | 2133CT1268.37.7 |
| Calculated MW | 20295 Da |
| Gene ID | 5368 |
|---|---|
| Other Names | Prepronociceptin, Nocistatin, Nociceptin, Orphanin FQ, PPNOC, Orphanin FQ2, PNOC, OFQ |
| Target/Specificity | This PNOC antibody is generated from a mouse immunized with a recombinant protein from human PNOC. |
| Dilution | WB~~1:8000 |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PNOC Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PNOC |
|---|---|
| Synonyms | OFQ |
| Function | [Nociceptin]: Ligand of the opioid receptor-like receptor OPRL1. It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development. |
| Cellular Location | Secreted. |
| Tissue Location | Predominantly expressed in the brain and spinal cord. Also expressed and secreted by peripheral blood neutrophils following degranulation. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Nociceptin: Ligand of the opioid receptor-like receptor OPRL1. It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development.
References
Mollereau C.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:8666-8670(1996).
Nothacker H.-P.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:8677-8682(1996).
Fiset M.E.,et al.Biochemistry 42:10498-10505(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
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