PLIN3 Antibody
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | O60664 |
Reactivity | Human |
Host | Mouse |
Clonality | monoclonal |
Isotype | IgG2a,k |
Clone/Animal Names | 1651CT755.90.33 |
Calculated MW | 47075 Da |
Gene ID | 10226 |
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Other Names | Perilipin-3, 47 kDa mannose 6-phosphate receptor-binding protein, 47 kDa MPR-binding protein, Cargo selection protein TIP47, Mannose-6-phosphate receptor-binding protein 1, Placental protein 17, PP17, PLIN3, M6PRBP1, TIP47 |
Target/Specificity | This PLIN3 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 1-434 amino acids from human PLIN3. |
Dilution | WB~~1:2000 |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PLIN3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PLIN3 |
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Synonyms | M6PRBP1, TIP47 {ECO:0000303|PubMed:95901 |
Function | Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets (PubMed:34077757). Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network (PubMed:9590177). |
Cellular Location | Lipid droplet. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Membrane associated on endosomes (PubMed:15545278). Detected in the envelope and the core of lipid bodies and in lipid sails (PubMed:15545278) |
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Provided below are standard protocols that you may find useful for product applications.
Background
Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network.
References
Diaz E.,et al.Cell 93:433-443(1998).
Than N.G.,et al.Eur. J. Biochem. 258:752-757(1998).
Than N.G.,et al.Tumor Biol. 20:184-192(1999).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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