CCR7 Antibody (N-term)
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | P32248 |
Reactivity | Human |
Predicted | Human |
Host | Mouse |
Clonality | monoclonal |
Isotype | IgG1,κ |
Clone/Animal Names | 1987CT875.52.22 |
Calculated MW | 42874 Da |
Gene ID | 1236 |
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Other Names | C-C chemokine receptor type 7, C-C CKR-7, CC-CKR-7, CCR-7, BLR2, CDw197, Epstein-Barr virus-induced G-protein coupled receptor 1, EBI1, EBV-induced G-protein coupled receptor 1, MIP-3 beta receptor, CD197, CCR7, CMKBR7, EBI1, EVI1 |
Target/Specificity | This CCR7 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 26-57 amino acids from the N-terminal region of human CCR7. |
Dilution | WB~~1:4000 |
Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CCR7 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CCR7 |
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Synonyms | CMKBR7, EBI1, EVI1 |
Function | Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions. |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Location | Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7 |
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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.
References
Birkenbach M.P.,et al.J. Virol. 67:2209-2220(1993).
Schweickart V.L.,et al.Genomics 23:643-650(1994).
Kopatz S.A.,et al.Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
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