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PSMC2 Antibody
Purified Mouse Monoclonal Antibody (Mab)
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- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P35998 |
| Other Accession | Q5E9F9, Q4R4R0, P46471 |
| Reactivity | Human |
| Predicted | Bovine, Monkey, Mouse |
| Host | Mouse |
| Clonality | monoclonal |
| Isotype | IgG1,k |
| Clone/Animal Names | 1851CT193.4.40 |
| Calculated MW | 48634 Da |
| Gene ID | 5701 |
|---|---|
| Other Names | 26S protease regulatory subunit 7, 26S proteasome AAA-ATPase subunit RPT1, Proteasome 26S subunit ATPase 2, Protein MSS1, PSMC2, MSS1 |
| Target/Specificity | This antibody is generated from a mouse immunized with a recombinant protein from human. |
| Dilution | WB~~1:2000 |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PSMC2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PSMC2 |
|---|---|
| Synonyms | MSS1 {ECO:0000303|PubMed:8500623} |
| Function | Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides. |
| Cellular Location | Cytoplasm. Note=Colocalizes with TRIM5 in cytoplasmic bodies |
Research Areas
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$ 385.00
Cat# AM8659b
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