human CD7 Antibody
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, E |
---|---|
Primary Accession | P09564 |
Reactivity | Human |
Host | Mouse |
Clonality | monoclonal |
Isotype | IgG1 |
Clone/Animal Names | T3-3A1 Equivalent |
Calculated MW | 25409 Da |
Gene ID | 924 |
---|---|
Dilution | FC~~1:50 |
Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | human CD7 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CD7 |
---|---|
Function | Transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors (PubMed:7506726). Plays a costimulatory role in T-cell activation upon binding to its ligand K12/SECTM1 (PubMed:10652336). In turn, mediates the production of cytokines such as IL-2 (PubMed:1709867). On resting NK-cells, CD7 activation results in a significant induction of interferon-gamma levels (PubMed:7506726). |
Cellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Location | Expressed on T-cells and natural killer (NK) cells and their precursors. |
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