ADK Antibody (N-term)
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P55263 |
Reactivity | Human |
Host | Mouse |
Clonality | monoclonal |
Isotype | IgG1,k |
Clone/Animal Names | 1103CT3.4.3 |
Calculated MW | 40545 Da |
Gene ID | 132 |
---|---|
Other Names | Adenosine kinase, AK, 2.7.1.20, Adenosine 5'-phosphotransferase, ADK |
Target/Specificity | This ADK antibody is generated from a mouse immunized with a recombinant protein between 1-345 amino acids from human ADK. |
Dilution | WB~~1:4000 IHC-P~~1:25 |
Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ADK Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ADK (HGNC:257) |
---|---|
Function | Catalyzes the phosphorylation of the purine nucleoside adenosine at the 5' position in an ATP-dependent manner. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides. |
Cellular Location | [Isoform 1]: Nucleus |
Tissue Location | Widely expressed. Highest level in placenta, liver, muscle and kidney. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.
References
Spychala J.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:1232-1237(1996).
Singh B.,et al.Eur. J. Biochem. 241:564-571(1996).
McNally T.,et al.Biochem. Biophys. Res. Commun. 231:645-650(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 429:375-381(2004).
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