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REG3G Antibody
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q6UW15 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | monoclonal |
| Isotype | IgG1,k |
| Clone/Animal Names | 1790CT313.66.2 |
| Calculated MW | 19330 Da |
| Gene ID | 130120 |
|---|---|
| Other Names | Regenerating islet-derived protein 3-gamma, REG-3-gamma, Pancreatitis-associated protein 1B, PAP-1B, Pancreatitis-associated protein IB, PAP IB, Regenerating islet-derived protein III-gamma, REG III, Reg III-gamma, Regenerating islet-derived protein 3-gamma 16.5 kDa form, Regenerating islet-derived protein 3-gamma 15 kDa form, REG3G, PAP1B |
| Target/Specificity | This REG3G antibody is generated from a mouse immunized with a recombinant protein of human REG3G. |
| Dilution | WB~~1:1000 IHC-P~~1:25 |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | REG3G Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | REG3G (HGNC:29595) |
|---|---|
| Synonyms | PAP1B |
| Function | Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. |
| Cellular Location | Secreted {ECO:0000250|UniProtKB:P42854}. Cytoplasm {ECO:0000250|UniProtKB:P42854} |
| Tissue Location | Predominantly expressed in pancreas, where it may be restricted to exocrine pancreas. Moderate expression levels in testis and weak in heart, kidney and placenta |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury.
References
Nata K.,et al.Gene 340:161-170(2004).
Laurine E.,et al.Biochim. Biophys. Acta 1727:177-187(2005).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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