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WBP2 Antibody (C-term)

Purified Mouse Monoclonal Antibody (Mab)

     
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  • WB - WBP2 Antibody (C-term) AM8599b
    All lanes : Anti-WBP2 Antibody (C-term) at 1:2000 dilution Lane 1: mouse heart lysate Lane 2: A549 whole cell lysate Lane 3: HL-60 whole cell lysate Lane 4: 293 whole cell lysate Lane 5: A2058 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 28/32 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q969T9
Reactivity Human, Mouse
Host Mouse
Clonality monoclonal
Isotype IgG1
Clone/Animal Names 932CT1.3.7
Calculated MW 28087 Da
Additional Information
Gene ID 23558
Other Names WW domain-binding protein 2, WBP-2, WBP2
Target/Specificity This WBP2 antibody is generated from a mouse immunized with a recombinant protein between 1-261 amino acids from the C-terminal region of human WBP2.
Dilution WB~~1:2000
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsWBP2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name WBP2 (HGNC:12738)
Function Acts as a transcriptional coactivator of estrogen and progesterone receptors (ESR1 and PGR) upon hormone activation (PubMed:16772533). In presence of estrogen, binds to ESR1-responsive promoters (PubMed:16772533). Synergizes with YAP1 to enhance PGR activity (PubMed:16772533). Modulates expression of post-synaptic scaffolding proteins via regulation of ESR1, ESR2 and PGR (By similarity).
Cellular Location Cytoplasm. Nucleus. Note=Translocates from cytoplasm to nucleus when phosphorylated.
Tissue Location Ubiquitous.
Research Areas
Citations (0)
citation

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References

Chen H.I.,et al.J. Biol. Chem. 272:17070-17077(1997).
Pirozzi G.,et al.J. Biol. Chem. 272:14611-14616(1997).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).

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$ 365.00
$ 140.00
Cat# AM8599b
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