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PBRM1 Antibody
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q86U86 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | monoclonal |
| Isotype | IgG1,k |
| Clone/Animal Names | 1636CT387.122.52 |
| Calculated MW | 192948 Da |
| Gene ID | 55193 |
|---|---|
| Other Names | Protein polybromo-1, hPB1, BRG1-associated factor 180, BAF180, Polybromo-1D, PBRM1, BAF180, PB1 |
| Target/Specificity | This PBRM1 antibody is generated from a mouse immunized with a recombinant proteinof human PBRM1. |
| Dilution | WB~~1:1000 |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PBRM1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PBRM1 |
|---|---|
| Synonyms | BAF180, PB1 |
| Function | Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. |
| Cellular Location | Nucleus |
| Tissue Location | Widely expressed.. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Acts as a negative regulator of cell proliferation.
References
Xue Y.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:13015-13020(2000).
Horikawa I.,et al.DNA Seq. 13:211-215(2002).
Sekine I.,et al.Oncogene 24:2735-2738(2005).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Lemon B.,et al.Nature 414:924-928(2001).
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