FAT1 Antibody
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q14517 |
Reactivity | Human |
Host | Mouse |
Clonality | monoclonal |
Isotype | IgG1,k |
Clone/Animal Names | 1634CT464.1.9 |
Calculated MW | 506273 Da |
Gene ID | 2195 |
---|---|
Other Names | Protocadherin Fat 1, Cadherin family member 7, Cadherin-related tumor suppressor homolog, Protein fat homolog, Protocadherin Fat 1, nuclear form, FAT1, CDHF7, FAT |
Target/Specificity | This FAT1 antibody is generated from a mouse immunized with a recombinant protein between 4203-4539 amino acids from human FAT1. |
Dilution | WB~~1:2000 |
Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | FAT1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FAT1 |
---|---|
Synonyms | CDHF7, FAT |
Function | [Protocadherin Fat 1]: Plays an essential role for cellular polarization, directed cell migration and modulating cell-cell contact. |
Cellular Location | [Protocadherin Fat 1]: Cell membrane; Single-pass type I membrane protein |
Tissue Location | Expressed in many epithelial and some endothelial and smooth muscle cells |
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Provided below are standard protocols that you may find useful for product applications.
Background
Plays an essential role for cellular polarization, directed cell migration and modulating cell-cell contact.
References
Dunne J.,et al.Genomics 30:207-223(1995).
Hillier L.W.,et al.Nature 434:724-731(2005).
Magg T.,et al.Exp. Cell Res. 307:100-108(2005).
Cantin G.T.,et al.J. Proteome Res. 7:1346-1351(2008).
Hou R.,et al.J. Biol. Chem. 284:6955-6965(2009).
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