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VAV1 Antibody
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P15498 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | monoclonal |
| Isotype | IgG1,k |
| Clone/Animal Names | 1582CT802.383.58 |
| Calculated MW | 98314 Da |
| Gene ID | 7409 |
|---|---|
| Other Names | Proto-oncogene vav, VAV1, VAV |
| Target/Specificity | This VAV1 antibody is generated from a mouse immunized with a recombinant protein of human VAV1. |
| Dilution | WB~~1:4000 |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | VAV1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | VAV1 |
|---|---|
| Synonyms | VAV |
| Function | Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation. |
| Tissue Location | Widely expressed in hematopoietic cells but not in other cell types |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
References
Coppola J.,et al.Cell Growth Differ. 2:95-105(1991).
Denkinger D.J.,et al.Biochim. Biophys. Acta 1491:253-262(2000).
Grimwood J.,et al.Nature 428:529-535(2004).
Katzav S.,et al.Mol. Cell. Biol. 11:1912-1920(1991).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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