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VAV1 Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
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  • WB - VAV1 Antibody AM8504b
    Anti-VAV1 Antibody at 1:4000 dilution + Raji whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 98 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P15498
Reactivity Human
Host Mouse
Clonality monoclonal
Isotype IgG1,k
Clone/Animal Names 1582CT802.383.58
Calculated MW 98314 Da
Additional Information
Gene ID 7409
Other Names Proto-oncogene vav, VAV1, VAV
Target/Specificity This VAV1 antibody is generated from a mouse immunized with a recombinant protein of human VAV1.
Dilution WB~~1:4000
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsVAV1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name VAV1
Synonyms VAV
Function Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
Tissue Location Widely expressed in hematopoietic cells but not in other cell types
Research Areas
Citations (0)
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Background

Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.

References

Coppola J.,et al.Cell Growth Differ. 2:95-105(1991).
Denkinger D.J.,et al.Biochim. Biophys. Acta 1491:253-262(2000).
Grimwood J.,et al.Nature 428:529-535(2004).
Katzav S.,et al.Mol. Cell. Biol. 11:1912-1920(1991).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 365.00
$ 140.00
Cat# AM8504b
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