EPHA6 Antibody
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q9UF33 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG1,k |
Clone/Animal Names | 1426CT591.205.91.119 |
Calculated MW | 116379 Da |
Gene ID | 285220 |
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Other Names | Ephrin type-A receptor 6, EPH homology kinase 2, EHK-2, EPH-like kinase 12, EK12, EPHA6, EHK2, HEK12 |
Target/Specificity | This EPHA6 antibody is generated from a mouse immunized with a recombinant protein. |
Dilution | WB~~1:1000 |
Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | EPHA6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | EPHA6 |
---|---|
Synonyms | EHK2, HEK12 |
Function | Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity). |
Cellular Location | Membrane; Single-pass type I membrane protein |
Tissue Location | Expressed in brain and testis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity).
References
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Hafner C.,et al.Clin. Chem. 50:490-499(2004).
Greenman C.,et al.Nature 446:153-158(2007).
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