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EPHA6 Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
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  • WB - EPHA6 Antibody AM8444b
    Western blot analysis of lysate from 293 cell line, using EPHA6 Antibody(Cat. #AM8444b). AM8444b was diluted at 1:1000. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysate at 20μg.
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  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9UF33
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1,k
Clone/Animal Names 1426CT591.205.91.119
Calculated MW 116379 Da
Additional Information
Gene ID 285220
Other Names Ephrin type-A receptor 6, EPH homology kinase 2, EHK-2, EPH-like kinase 12, EK12, EPHA6, EHK2, HEK12
Target/Specificity This EPHA6 antibody is generated from a mouse immunized with a recombinant protein.
Dilution WB~~1:1000
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsEPHA6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EPHA6
Synonyms EHK2, HEK12
Function Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed in brain and testis.
Research Areas
Citations (0)
citation

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Background

Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity).

References

Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Hafner C.,et al.Clin. Chem. 50:490-499(2004).
Greenman C.,et al.Nature 446:153-158(2007).

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$ 365.00
$ 140.00
Cat# AM8444b
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