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RPS6 Antibody (N-term)
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, IF, FC, WB, E |
|---|---|
| Primary Accession | P62753 |
| Other Accession | P62755, P62754, Q4R4K6, G1TM55 |
| Reactivity | Human, Rat |
| Predicted | Monkey, Mouse, Rabbit |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Clone/Animal Names | 981CT2.1.1 |
| Calculated MW | 28681 Da |
| Gene ID | 6194 |
|---|---|
| Other Names | 40S ribosomal protein S6, Phosphoprotein NP33, RPS6 |
| Target/Specificity | This RPS6 antibody is generated from a mouse immunized with RPS6 recombinant protein. |
| Dilution | IF~~1:25 WB~~1:1000 IHC-P~~1:25 FC~~1:25 |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RPS6 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RPS6 {ECO:0000303|PubMed:29563586, ECO:0000312|HGNC:HGNC:10429} |
|---|---|
| Function | Component of the 40S small ribosomal subunit (PubMed:23636399, PubMed:8706699). Plays an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA (PubMed:17220279). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797). |
| Cellular Location | Cytoplasm. Nucleus, nucleolus |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA.
References
Lott J.B.,et al.Gene 65:31-39(1988).
Heinze H.,et al.J. Biol. Chem. 263:4139-4144(1988).
Antoine M.,et al.Hum. Mol. Genet. 1:565-570(1992).
Pata I.,et al.Gene 121:387-392(1992).
Shichijo S.,et al.Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
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