CDA Antibody (Center)
Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | P32320 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG1 |
Clone/Animal Names | 921CT14.2.1 |
Calculated MW | 16185 Da |
Gene ID | 978 |
---|---|
Other Names | Cytidine deaminase, Cytidine aminohydrolase, CDA, CDD |
Target/Specificity | Purified His-tagged CDA protein was used to produced this monoclonal antibody. |
Dilution | WB~~1:1000 |
Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CDA Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CDA (HGNC:1712) |
---|---|
Synonyms | CDD |
Function | This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. |
Tissue Location | Highly expressed in granulocytes while expression is very low in fibroblasts, chondrocytes, monocytes, and T- as well as B-cell lines |
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Provided below are standard protocols that you may find useful for product applications.
Background
This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
References
Laliberte J., et al. Cancer Res. 54:5401-5407(1994).
Demontis S., et al. Biochim. Biophys. Acta 1443:323-333(1998).
Gran C., et al. Blood 91:4127-4135(1998).
Gregory S.G., et al. Nature 441:315-321(2006).
Kuhn K., et al. Biochem. Biophys. Res. Commun. 190:1-7(1993).
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