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CDX1 Antibody (C-term)
Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P47902 |
| Reactivity | Human, Mouse |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Clone/Animal Names | 937CT11.6.2 |
| Calculated MW | 28138 Da |
| Gene ID | 1044 |
|---|---|
| Other Names | Homeobox protein CDX-1, Caudal-type homeobox protein 1, CDX1 |
| Target/Specificity | Purified His-tagged CDX1 protein was used to produced this monoclonal antibody. |
| Dilution | WB~~1:1000-1:2000 |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CDX1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CDX1 |
|---|---|
| Function | Plays a role in transcriptional regulation (PubMed:24623306). Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the PRKD1 promoter in colorectal cancer (CRC) cells (PubMed:24623306). Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA (PubMed:28473536). |
| Cellular Location | Nucleus. |
| Tissue Location | Intestinal epithelium. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Could play a role in the terminal differentiation of the intestine.
References
Bonner C.A., et al. Genomics 28:206-211(1995).
Mallo G.V., et al. Int. J. Cancer 74:35-44(1997).
Malakooti J., et al. Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
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