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UBL5 Antibody
Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9BZL1 |
| Other Accession | Q9EPV8, Q3T0Z3, NP_001041706.1, NP_077268.1 |
| Reactivity | Human, Mouse |
| Predicted | Bovine |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Clone/Animal Names | 429CT16.3.1 |
| Calculated MW | 8547 Da |
| Gene ID | 59286 |
|---|---|
| Other Names | Ubiquitin-like protein 5, UBL5 |
| Target/Specificity | Purified His-tagged UBL5 protein(Fragment) was used to produced this monoclonal antibody. |
| Dilution | WB~~1:100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | UBL5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | UBL5 |
|---|---|
| Function | Ubiquitin-like protein that plays a role in cell proliferation and sister chromatid cohesion by associating with spliceosomal proteins (PubMed:25092792). Participates thereby in pre- mRNA splicing by maintaining spliceosome integrity. Promotes the functional integrity of the Fanconi anemia DNA repair pathway by interacting with FANCI component and subsequently mediating the formation of FANCI homodimers (PubMed:25862789). Plays also a protective role against ER stress-induced apoptosis (PubMed:37315790). |
| Cellular Location | Cytoplasm. Nucleus. Nucleus, Cajal body |
| Tissue Location | Ubiquitous. Highest level of expression in heart, skeletal muscle, kidney, liver, iris and lymphoblasts |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Ubiquitin-like proteins (UBLs) are thought to be reversible modulators of protein function rather than protein degraders like ubiquitin (MIM 191339).
References
de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009)
Sentinelli, F., et al. J. Pediatr. Endocrinol. Metab. 21(12):1139-1145(2008)
Bozaoglu, K., et al. Hum. Biol. 78(2):147-159(2006)
Wilkinson, C.R., et al. Curr. Biol. 14(24):2283-2288(2004)
Jowett, J.B., et al. Diabetes 53(9):2467-2472(2004)
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