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TNFSF4 Antibody (Ascites)
Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P23510 |
| Other Accession | NP_003317.1 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgM |
| Clone/Animal Names | 362CT19.3.3 |
| Calculated MW | 21050 Da |
| Antigen Region | 97-125 aa |
| Gene ID | 7292 |
|---|---|
| Other Names | Tumor necrosis factor ligand superfamily member 4, Glycoprotein Gp34, OX40 ligand, OX40L, TAX transcriptionally-activated glycoprotein 1, CD252, TNFSF4, TXGP1 |
| Target/Specificity | This TNFSF4 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 97-125 amino acids from human TNFSF4. |
| Dilution | WB~~1:500~4000 |
| Format | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TNFSF4 Antibody (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TNFSF4 |
|---|---|
| Synonyms | TXGP1 |
| Function | Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. |
| Cellular Location | Membrane; Single-pass type II membrane protein. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.
References
Karulf, M., et al. J. Immunol. 185(8):4856-4862(2010)
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Mosbruger, T.L., et al. J. Infect. Dis. 201(9):1371-1380(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
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