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SYP Antibody (C-term) (ascites)

Mouse Monoclonal Antibody (Mab)

     
  • WB - SYP Antibody (C-term) (ascites) AM1945a
    SYP Antibody (C-term) (Cat. #AM1945a) western blot analysis in mouse brain tissue lysates (35μg/lane).This demonstrates the SYP antibody detected the SYP protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P08247
Other Accession P07825, Q62277, NP_003170.1
Reactivity Mouse
Predicted Rat
Host Mouse
Clonality Monoclonal
Isotype IgM
Clone/Animal Names 298CT23.4.4
Calculated MW 33845 Da
Antigen Region 225-253 aa
Additional Information
Gene ID 6855
Other Names Synaptophysin, Major synaptic vesicle protein p38, SYP
Target/Specificity This SYP antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 225-253 amino acids from the C-terminal region of human SYP.
Dilution WB~~1:100~4000
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSYP Antibody (C-term) (ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SYP
Function Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).
Cellular Location Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Synapse, synaptosome
Tissue Location Expressed in the brain, with expression in the hippocampus, the neuropil in the dentate gyrus, where expression is higher in the outer half of the molecular layer than in the inner half, and in the neuropil of CA4 and CA3 (PubMed:8838578). Expressed in the putamen (at protein level) (PubMed:17296554)
Research Areas
Citations (0)
citation

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Background

Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells.[supplied by OMIM].

References

Ishida, M., et al. Oncol. Rep. 22(4):733-737(2009)
Sterlacci, W., et al. Virchows Arch. 455(2):125-132(2009)
Head, E., et al. Neurobiol. Aging 30(7):1125-1134(2009)
Gulubova, M., et al. J. Gastroenterol. Hepatol. 23(10):1574-1585(2008)
Glantz, L.A., et al. Neuroscience 149(3):582-591(2007)

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$ 182.50
Cat# AM1945a
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