Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
Rat Serpinh1 Antibody (Center)
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | P29457 |
| Other Accession | P19324, P50454, Q2KJH6 |
| Reactivity | Human, Rat |
| Predicted | Bovine, Mouse |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Clone/Animal Names | 134CT3.1.1 |
| Calculated MW | 46518 Da |
| Antigen Region | 222-251 aa |
| Gene ID | 29345 |
|---|---|
| Other Names | Serpin H1, 47 kDa heat shock protein, Collagen-binding protein, Colligin, GP46, Serpinh1, Cbp1, Hsp47 |
| Target/Specificity | This Rat Serpinh1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 222-251 amino acids from the Central region of rat Serpinh1. |
| Dilution | WB~~1:500~1000 IHC-P~~1:50~100 |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Rat Serpinh1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Serpinh1 |
|---|---|
| Synonyms | Cbp1, Hsp47 |
| Function | Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen. |
| Cellular Location | Endoplasmic reticulum lumen. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Localization of HSP47 mRNA in murine bleomycin-induced pulmonary fibrosis. Kakugawa T, et al. Virchows Arch, 2010 Mar. PMID 20094730. The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. Sansom SN, et al. PLoS Genet, 2009 Jun. PMID 19521500. Fog2 is critical for cardiac function and maintenance of coronary vasculature in the adult mouse heart. Zhou B, et al. J Clin Invest, 2009 Jun. PMID 19411759. Adenovirus-mediated RNA interference against collagen-specific molecular chaperone 47-KDa heat shock protein suppresses scar formation on mouse wounds. Wang Z, et al. Cell Biol Int, 2008 May. PMID 18093850. Type I collagen in Hsp47-null cells is aggregated in endoplasmic reticulum and deficient in N-propeptide processing and fibrillogenesis. Ishida Y, et al. Mol Biol Cell, 2006 May. PMID 16525016.
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
