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DRP-2 Antibody

Mouse Monoclonal Antibody (Mab)

     
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  • WB - DRP-2 Antibody AM1131a
    All lanes : Anti-DRP-2 Antibody at 1:128000 dilution Lane 1: human brain lysate Lane 2: mouse brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 62 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
    detail
  • WB - DRP-2 Antibody AM1131a
    All lanes : Anti-DRP-2 Antibody at 1:8000 dilution Lane 1: NIH/3T3 whole cell lysate Lane 2: Mouse brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 62, 58 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q16555
Other Accession P47942, O08553, Q90635, O02675
Reactivity Human, Mouse
Predicted Bovine, Chicken, Rat
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Clone/Animal Names 33CT11.7.6
Calculated MW 62294 Da
Antigen Region 463-492 aa
Additional Information
Gene ID 1808
Other Names Dihydropyrimidinase-related protein 2, DRP-2, Collapsin response mediator protein 2, CRMP-2, N2A3, Unc-33-like phosphoprotein 2, ULIP-2, DPYSL2, CRMP2, ULIP2
Target/Specificity This DRP-2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 463-492 amino acids from human DRP-2.
Dilution WB~~1:8000
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDRP-2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DPYSL2
Synonyms CRMP2, ULIP2
Function Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.
Cellular Location Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Membrane. Note=Tightly but non-covalently associated with membranes
Tissue Location Ubiquitous.
Research Areas
Citations (0)
citation

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References

A two-stage case-control association study of the dihydropyrimidinase-like 2 gene (DPYSL2) with schizophrenia in Japanese subjects. Koide T, et al. J Hum Genet, 2010 Jul. PMID 20414250. Sex-specific proteome differences in the anterior cingulate cortex of schizophrenia. Martins-de-Souza D, et al. J Psychiatr Res, 2010 Apr 8. PMID 20381070. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614. Collapsin response mediator protein-2 regulates neurite formation by modulating tubulin GTPase activity. Chae YC, et al. Cell Signal, 2009 Dec. PMID 19666111. CRMP-2 directly binds to cytoplasmic dynein and interferes with its activity. Arimura N, et al. J Neurochem, 2009 Oct. PMID 19659462.

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$ 365.00
$ 140.00
Cat# AM1131a
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