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Anti-ATP1A1 Antibody (aa800-850)

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, FC
Primary Accession P05023
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 112896 Da
Dilution Flo, IHC-P (10 µg/ml), WB (0.5 - 1 µg/ml)
Additional Information
Gene ID 476
Alias Symbol ATP1A1
Other Names ATP1A1, Na+, K+ ATPase alpha subunit, Na, K-ATPase alpha-1 subunit, Na+/K+ ATPase 1, Sodium pump 1, Sodium pump subunit alpha-1
Target/Specificity Endogenous levels of human, mouse, and rat ATP1A1.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-ATP1A1 Antibody (aa800-850) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATP1A1
Function This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients (PubMed:29499166, PubMed:30388404). Could also be part of an osmosensory signaling pathway that senses body-fluid sodium levels and controls salt intake behavior as well as voluntary water intake to regulate sodium homeostasis (By similarity).
Cellular Location Cell membrane {ECO:0000250|UniProtKB:Q8VDN2}; Multi-pass membrane protein. Basolateral cell membrane {ECO:0000250|UniProtKB:P06685}; Multi-pass membrane protein. Cell membrane, sarcolemma; Multi-pass membrane protein. Cell projection, axon {ECO:0000250|UniProtKB:P06685}. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Research Areas
Citations (0)
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$ 467.50
Cat# ALS18463
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