Anti-MAP3K13 / LZK Antibody (Internal)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IP |
---|---|
Primary Accession | O43283 |
Predicted | Human, Mouse, Rat, Rabbit, Chicken, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 108296 Da |
Dilution | IHC-P (1:100), IP (1:10 - 1:100), WB (1:500 - 1:1000) |
Gene ID | 9175 |
---|---|
Alias Symbol | MAP3K13 |
Other Names | MAP3K13, Leucine zipper-bearing kinase, LZK, Mixed lineage kinase, MLK, MEKK13 |
Target/Specificity | Recognizes endogenous levels of LZK protein. |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-MAP3K13 / LZK Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MAP3K13 (HGNC:6852) |
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Function | Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB- containing complex that phosphorylates inhibitors of NF-kappa-B. |
Cellular Location | Cytoplasm. Membrane; Peripheral membrane protein |
Tissue Location | Expressed in the adult brain, liver, placenta and pancreas, with expression strongest in the pancreas |
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