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Anti-MECP2 Antibody

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P51608
Predicted Human, Mouse, Rat, Monkey, Chimpanzee, Bovine, Horse, Dog
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 52441 Da
Dilution IHC-P (5 µg/ml), WB (0.5 µg/ml)
Additional Information
Gene ID 4204
Alias Symbol MECP2
Other Names MECP2, AUTSX3, Methyl-CpG-binding protein 2, MRX16, MRX79, MRXSL, RTT, RTS, MeCp-2 protein, RS, MRXS13, PPMX
Target/Specificity The antibody detects methyl CpG binding protein 2 (MeCP2) from human, mouse and rat cells and tissues. It has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~56 kD protein representing MeCP2 from AtT20 ce ...
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-MECP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MECP2
Function Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)- containing DNA, with a preference for 5-methylcytosine (5mC).
Cellular Location Nucleus {ECO:0000250|UniProtKB:Q9Z2D6}. Note=Colocalized with methyl-CpG in the genome. Colocalized with TBL1X to the heterochromatin foci.
Tissue Location Present in all adult somatic tissues tested.
Research Areas
Citations (0)
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$ 467.50
Cat# ALS18280
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