Anti-FGF19 Antibody (clone FG369-1)
Mouse Anti Human Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | O95750 |
Predicted | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG1,k |
Clone Names | FG369-1 |
Calculated MW | 24003 Da |
Dilution | ELISA (1:2000 - 1:5000), IHC-P (15 µg/ml), WB (1:2000 - 1:5000) |
Gene ID | 9965 |
---|---|
Alias Symbol | FGF19 |
Other Names | FGF19, Fibroblast growth factor 19, FGF-19 |
Target/Specificity | Recognizes human FGF-19. Detects a band of ~25kDa by Western blot. |
Reconstitution & Storage | Protein G purified |
Precautions | Anti-FGF19 Antibody (clone FG369-1) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FGF19 |
---|---|
Function | Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4. |
Cellular Location | Secreted. |
Tissue Location | Expressed in fetal brain, cartilage, retina, and adult gall bladder. |
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