Anti-IGFBP3 Antibody (aa130-179)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P17936 |
Predicted | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 31674 Da |
Dilution | ELISA, IHC-P (1:50), WB |
Gene ID | 3486 |
---|---|
Alias Symbol | IGFBP3 |
Other Names | IGFBP3, Binding protein 29, Binding protein 53, BP-53, IGF-binding protein 3, IGFBP-3, IBP-3, IBP3 |
Target/Specificity | IGFBP-3 antibody detects endogenous levels of IGFBP-3. |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-IGFBP3 Antibody (aa130-179) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | IGFBP3 |
---|---|
Synonyms | IBP3 |
Function | IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. Inhibits the positive effect of humanin on insulin sensitivity (PubMed:19623253). Promotes testicular germ cell apoptosis (PubMed:19952275). |
Cellular Location | Secreted. |
Tissue Location | Expressed by most tissues. Present in plasma. |
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