Anti-ADRB2 Antibody (N-Terminus)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | P07550 |
Predicted | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 46459 Da |
Dilution | IHC-P (2.8 - 4.6 µg/ml) |
Gene ID | 154 |
---|---|
Alias Symbol | ADRB2 |
Other Names | ADRB2, ADRB2R, Adrenoceptor beta 2, surface, ADRBR, B2AR, Beta-2 adrenoceptor, Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, BETA2AR, BAR, Adrenergic beta-2 receptor, Catecholamine receptor |
Target/Specificity | Human ADRB2. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-ADRB2 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ADRB2 |
---|---|
Synonyms | ADRB2R, B2AR |
Function | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine. |
Cellular Location | Cell membrane; Multi-pass membrane protein. Early endosome. Golgi apparatus. Note=Colocalizes with VHL at the cell membrane (PubMed:19584355). Activated receptors are internalized into endosomes prior to their degradation in lysosomes (PubMed:20559325) Activated receptors are also detected within the Golgi apparatus (PubMed:27481942). |
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