Anti-HP / Haptoglobin Antibody (aa19-406)
Mouse Anti Human Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P00738 |
Predicted | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG1 |
Calculated MW | 45205 Da |
Dilution | ELISA, IHC-P (5 µg/ml), WB (1:1000) |
Gene ID | 3240 |
---|---|
Alias Symbol | HP |
Other Names | HP, Binding peptide, Haptoglobin alpha(1S)-beta, Haptoglobin, beta polypeptide, Haptoglobin, Haptoglobin alpha(2FS)-beta, Haptoglobin, alpha polypeptide, HP2ALPHA2, BP, Zonulin, HPA1S |
Target/Specificity | Anti-Haptoglobin recognizes Haptoglobin expression in BGC823 whole cell lysate. |
Reconstitution & Storage | Affinity purified |
Precautions | Anti-HP / Haptoglobin Antibody (aa19-406) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | HP |
---|---|
Function | As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity, and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. |
Cellular Location | Secreted. |
Tissue Location | Expressed by the liver and secreted in plasma. |
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