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Anti-TF / Transferrin Antibody (N-Terminus, clone 2A2)

Mouse Anti Human Monoclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
IHC-P, E, FuncS
Primary Accession P02787
Predicted Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 2A2
Calculated MW 77050 Da
Dilution ELISA (1:500 - 1:5000), Func, IHC-P (10 µg/ml)
Additional Information
Gene ID 7018
Alias Symbol TF
Other Names TF, PRO1557, Serotransferrin, Siderophilin, TFQTL1, Beta-1 metal-binding globulin, Transferrin, PRO2086
Target/Specificity Recognizes the N-terminal domain of human transferrin. In functional assaysinhibits the proliferation of Con-A stimulated blood lymphocytes. Removal of sodium azide is recommended prior to use in functional assays.
Reconstitution & Storage Protein A purified
PrecautionsAnti-TF / Transferrin Antibody (N-Terminus, clone 2A2) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TF (HGNC:11740)
Function Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. (Microbial infection) Serves as an iron source for parasite T.brucei (strain 427), which capture TF via its own transferrin receptor ESAG6:ESAG7 and extract its iron for its own use.
Cellular Location Secreted.
Tissue Location Expressed by the liver and secreted in plasma.
Research Areas
Citations (0)
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$ 467.50
Cat# ALS17625
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