Anti-NOS3 / eNOS Antibody
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
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Primary Accession | P29474 |
Predicted | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 133275 Da |
Dilution | IHC-P (10 µg/ml), WB |
Gene ID | 4846 |
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Alias Symbol | NOS3 |
Other Names | NOS3, Constitutive NOS, CNOS, Endothelial NOS, ECNOS, NOS type III, NOSIII, EC-NOS, ENOS, Nitric oxide synthase 3 |
Target/Specificity | eNOS |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-NOS3 / eNOS Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NOS3 (HGNC:7876) |
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Function | Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway (PubMed:1378832). NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. |
Cellular Location | Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Note=Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity |
Tissue Location | Platelets, placenta, liver and kidney. |
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