Anti-GPR52 Antibody (N-Terminus)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| IHC-P |
---|---|
Primary Accession | Q9Y2T5 |
Predicted | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 41354 Da |
Dilution | IHC-P (3 - 9 µg/ml) |
Gene ID | 9293 |
---|---|
Alias Symbol | GPR52 |
Other Names | GPR52, Axor10, G protein-coupled receptor 52 |
Target/Specificity | Human GPR52. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-GPR52 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GPR52 {ECO:0000303|PubMed:9931487, ECO:0000312|HGNC:HGNC:4508} |
---|---|
Function | Gs-coupled receptor activated by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization (PubMed:24587241). May play a role in locomotor activity through modulation of dopamine, NMDA and ADORA2A-induced locomotor activity. These behavioral changes are accompanied by modulation of the dopamine receptor signaling pathway in striatum (PubMed:24587241). Modulates HTT level via cAMP-dependent but PKA independent mechanisms throught activation of RAB39B that translocates HTT to the endoplasmic reticulum, thus avoiding proteasome degradation (PubMed:25738228). |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Location | Expressed in brain, especially in striatum. |

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.

If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.