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Anti-TRIM29 Antibody (aa4-129)

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q14134
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 65835 Da
Dilution IHC-P (5 µg/ml), WB
Additional Information
Gene ID 23650
Alias Symbol TRIM29
Other Names TRIM29, ATDC, Tripartite motif containing 29, Tripartite motif-containing 29
Target/Specificity Human TRIM29
Reconstitution & Storage PBS, 0.05% sodium azide. Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PrecautionsAnti-TRIM29 Antibody (aa4-129) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TRIM29
Synonyms ATDC
Function Plays a crucial role in the regulation of macrophage activation in response to viral or bacterial infections within the respiratory tract. Mechanistically, TRIM29 interacts with IKBKG/NEMO in the lysosome where it induces its 'Lys-48' ubiquitination and subsequent degradation. In turn, the expression of type I interferons and the production of pro-inflammatory cytokines are inhibited. Additionally, induces the 'Lys-48' ubiquitination of STING1 in a similar way, leading to its degradation.
Cellular Location Cytoplasm. Lysosome. Note=Colocalizes with intermediate filaments
Tissue Location Expressed in placenta, prostate and thymus.
Research Areas
Citations (0)
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$ 467.50
Cat# ALS17395
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