Anti-MLZE Antibody (aa109-158)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q9BYG8 |
Predicted | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 57692 Da |
Dilution | ELISA, IHC-P (1:200), WB |
Gene ID | 56169 |
---|---|
Alias Symbol | GSDMC |
Other Names | GSDMC, Gasdermin C, MLZE, Gasdermin-C |
Target/Specificity | GSDMC Antibody detects endogenous levels of GSDMC. |
Reconstitution & Storage | PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C. |
Precautions | Anti-MLZE Antibody (aa109-158) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GSDMC {ECO:0000303|PubMed:17350798, ECO:0000312|HGNC:HGNC:7151} |
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Function | [Gasdermin-C]: This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-C, N-terminal) binds to membranes and forms pores, triggering pyroptosis. |
Cellular Location | [Gasdermin-C]: Cytoplasm, cytosol |
Tissue Location | Expressed mainly in trachea and spleen (PubMed:11223543). In the esophagus, expressed in differentiating cells and probably in differentiated cells. Also detected in gastric epithelium (PubMed:19051310). |
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