PSAT1 Antibody (aa48-328)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, ICC |
---|---|
Primary Accession | Q9Y617 |
Other Accession | 29968 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 40423 Da |
Dilution | ICC (1:100 - 1:1000), IHC-P (5 µg/ml), WB (1:500 - 1:3000), |
Gene ID | 29968 |
---|---|
Other Names | PSAT1, EPIP, Phosphoserine aminotransferase, PSA, PSAT |
Target/Specificity | Human PSAT1 |
Reconstitution & Storage | 0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal. Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles. |
Precautions | PSAT1 Antibody (aa48-328) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PSAT1 (HGNC:19129) |
---|---|
Synonyms | PSA |
Function | Involved in L-serine biosynthesis via the phosphorylated pathway, a three-step pathway converting the glycolytic intermediate 3- phospho-D-glycerate into L-serine. Catalyzes the second step, that is the pyridoxal 5'-phosphate-dependent transamination of 3- phosphohydroxypyruvate and L-glutamate to O-phosphoserine (OPS) and alpha-ketoglutarate. |
Tissue Location | Expressed at high levels in the brain, liver, kidney and pancreas, and very weakly expressed in the thymus, prostate, testis and colon. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
References
Baek J.Y.,et al.Biochem. J. 373:191-200(2003).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Gauci S.,et al.Anal. Chem. 81:4493-4501(2009).
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