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SLC33A1 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, ICC, FC |
|---|---|
| Primary Accession | O00400 |
| Other Accession | 9197 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 60909 Da |
| Dilution | Flo (1:500), ICC (1:500), IHC-P (1:100), |
| Gene ID | 9197 |
|---|---|
| Other Names | SLC33A1, ACATN, Acetyl-CoA transporter 1, Acetyl-CoA transporter, CCHLND, Acetyl-Coenzyme A transporter, SPG42, AT-1, AT1 |
| Target/Specificity | Human SLC33A1 |
| Reconstitution & Storage | PBS, pH 7.2, 50% glycerol. Store at -20°C. |
| Precautions | SLC33A1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SLC33A1 (HGNC:95) |
|---|---|
| Synonyms | ACATN, AT1 |
| Function | Acetyl-CoA transporter that mediates active acetyl-CoA import through the endoplasmic reticulum (ER) membrane into the ER lumen where specific ER-based acetyl-CoA:lysine acetyltransferases are responsible for the acetylation of ER-based protein substrates, such as BACE1 (PubMed:20826464, PubMed:24828632). Necessary for O-acetylation of gangliosides (PubMed:9096318). |
| Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein |
| Tissue Location | Ubiquitous. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. With strongest signals in pancreas. |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Probable acetyl-CoA transporter necessary for O- acetylation of gangliosides.
References
Kanamori A.,et al.Proc. Natl. Acad. Sci. U.S.A. 94:2897-2902(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Sjoeblom T.,et al.Science 314:268-274(2006).
Lin P.,et al.Am. J. Hum. Genet. 83:752-759(2008).
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