Register or Login
All
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
COVID19
>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Immunity   >   IL1RL2 Antibody (Internal)   

IL1RL2 Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • IHC - IL1RL2 Antibody (Internal) ALS16774
    Anti-IL1RL2 antibody IHC staining of human heart.
    detail
  • IF - IL1RL2 Antibody (Internal) ALS16774
    Immunofluorescence of IL-1RL2 in human small intestine tissue with IL-1RL2 antibody at 20 ug/ml.
    detail
  • WB - IL1RL2 Antibody (Internal) ALS16774
    Western blot analysis of IL-1RL2 in human small intestine lysate with IL-1RL2 antibody at (A) 1...
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q9HB29
Other Accession 8808
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 65405 Da
Dilution IF (20 µg/ml), IHC-P (10 µg/ml), WB (1 - 2 µg/ml),
Additional Information
Gene ID 8808
Other Names IL1RL2, IL-1Rrp2, IL1R-rp2, IL1RRP2, Interleukin 1 receptor-like 2, Interleukin-1 receptor-like 2, IL-36R
Target/Specificity IL-1RL2 antibody is human, mouse and rat reactive. At least three isoforms of IL-1RL2 are known to exist; this antibody will detect all three isoforms. IL-1RL2 antibody is predicted to not cross-react with IL-1R or IL-1RL1.
Reconstitution & Storage PBS, 0.02% sodium azide. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsIL1RL2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL1RL2
Synonyms IL1RRP2
Function Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36- dependent activation of NF-kappa-B, MAPK and other pathways (By similarity). The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed in synovial fibroblasts and articular chondrocytes. Expressed in keratinocytes and monocyte-derived dendritic cells. Expressed in monocytes and myeloid dendritic cells; at protein level.
Research Areas
Citations (0)
citation

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abcepta antibody to
info@abcepta.com, and receive a free "I Love Antibodies" mug.

Background

Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways (By similarity). The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL- 23/IL-17/IL-22 pathway.

References

Born T.L.,et al.J. Biol. Chem. 275:29946-29954(2000).
Lovenberg T.W.,et al.J. Neuroimmunol. 70:113-122(1996).
Hillier L.W.,et al.Nature 434:724-731(2005).
Debets R.,et al.J. Immunol. 167:1440-1446(2001).
Magne D.,et al.Arthritis Res. Ther. 8:R80-R80(2006).

FeedBack
Abcepta welcomes feedback from its customers.

If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at tech@abcepta.com.

$ 467.50
Cat# ALS16774
Size:
Quantity:
Availability: 5 days
Bulk Size

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaCentral AmericaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSouth KoreaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamWorldwideOthers
Abcepta, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Terms & Conditions
"