CD1C Antibody (clone 4C7)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF |
---|---|
Primary Accession | P29017 |
Other Accession | 911 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG1 |
Clone Names | 4C7 |
Calculated MW | 37654 Da |
Dilution | IF (1:100), IHC-P (10 µg/ml), WB (1:500 - 1:2000), |
Gene ID | 911 |
---|---|
Other Names | CD1C, BDCA1, CD1, CD1c molecule, CD1C antigen, c polypeptide, CD1c antigen, R7 |
Target/Specificity | Human CD1C |
Reconstitution & Storage | PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing. |
Precautions | CD1C Antibody (clone 4C7) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CD1C |
---|---|
Function | Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. |
Cellular Location | Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein Lysosome. Note=Subject to intracellular trafficking between the cell membrane and endosomes |
Tissue Location | Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
References
Martin L.H.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:9189-9193(1987).
Aruffo A.,et al.J. Immunol. 143:1723-1730(1989).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
Han M.,et al.Tissue Antigens 54:122-127(1999).
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