NCAM / CD56 Antibody (clone 123C3)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, ICC, IHC-F |
---|---|
Primary Accession | P13591 |
Other Accession | 4684 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG1 |
Clone Names | 123C3 |
Calculated MW | 94574 Da |
Dilution | IHC-Fr (1:100 - 1:200), IHC-P (10 µg/ml), WB (1:100 - 1:1000), |
Gene ID | 4684 |
---|---|
Other Names | NCAM1, CD56, CD56 antigen, MSK39, NCAM-1, N-CAM-1, NCAM |
Target/Specificity | Recognizes an epitope in the NCAM exons 11-13 which is dependent on an intact conformation of the first fibronectin type-III homologous domain encoded by these exons. Stains NCAM which is present in small cell lung cancer and lung carcinoids. It also ... |
Reconstitution & Storage | PBS containing 0.09% sodium azide. Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
Precautions | NCAM / CD56 Antibody (clone 123C3) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NCAM1 (HGNC:7656) |
---|---|
Synonyms | NCAM |
Function | This protein is a cell adhesion molecule involved in neuron- neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. (Microbial infection) Acts as a receptor for Zika virus. |
Cellular Location | [Isoform 1]: Cell membrane; Single-pass type I membrane protein [Isoform 3]: Cell membrane; Lipid-anchor, GPI- anchor [Isoform 5]: Secreted. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.
References
Barton C.H.,et al.Development 104:165-173(1988).
Lanier L.L.,et al.J. Immunol. 146:4421-4426(1991).
Saito S.,et al.Lung Cancer 10:307-318(1994).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
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