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LMNB1 / Lamin B1 Antibody (aa289-574)

Rabbit Polyclonal Antibody

     
  • WB - LMNB1 / Lamin B1 Antibody (aa289-574) ALS16195
    Sample (30 ug whole cell lysate).
    detail
  • WB - LMNB1 / Lamin B1 Antibody (aa289-574) ALS16195
    Sample (30 ug of whole cell lysate). A: NIH-3T3. 7.5% SDS PAGE. Lamin B1 antibody diluted at 1:5000.
    detail
  • IHC - LMNB1 / Lamin B1 Antibody (aa289-574) ALS16195
    Anti-LMNB1 / Lamin B1 antibody IHC staining of human spleen.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P20700
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 66kDa
Dilution IHC-P (7.5 µg/ml), WB (1:1000-1:10000),
Additional Information
Gene ID 4001
Other Names Lamin-B1, LMNB1, LMN2, LMNB
Target/Specificity Human Lamin B1
Reconstitution & Storage Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
PrecautionsLMNB1 / Lamin B1 Antibody (aa289-574) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LMNB1
Synonyms LMN2, LMNB
Function Lamins are intermediate filament proteins that assemble into a filamentous meshwork, and which constitute the major components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane (PubMed:28716252, PubMed:32910914). Lamins provide a framework for the nuclear envelope, bridging the nuclear envelope and chromatin, thereby playing an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics (PubMed:28716252, PubMed:32910914). The structural integrity of the lamina is strictly controlled by the cell cycle, as seen by the disintegration and formation of the nuclear envelope in prophase and telophase, respectively (PubMed:28716252, PubMed:32910914).
Cellular Location Nucleus lamina
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.

References

Pollard K.M.,et al.Mol. Cell. Biol. 10:2164-2175(1990).
Lin F.,et al.Genomics 27:230-236(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Bienvenut W.V.,et al.Submitted (DEC-2008) to UniProtKB.

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$ 467.50
Cat# ALS16195
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