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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Viral process   >   KRT18 / CK18 / Cytokeratin 18 Antibody (clone DC-10, Azide-free)   

KRT18 / CK18 / Cytokeratin 18 Antibody (clone DC-10, Azide-free)

Mouse Monoclonal Antibody

     
  • IHC - KRT18 / CK18 / Cytokeratin 18 Antibody (clone DC-10, Azide-free) ALS16044
    Anti-KRT18 / CK18 / Cytokeratin 18 antibody IHC staining of human colon.
    detail
  • IHC - KRT18 / CK18 / Cytokeratin 18 Antibody (clone DC-10, Azide-free) ALS16044
    Anti-KRT18 / CK18 / Cytokeratin 18 antibody IHC staining of human prostate.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession P05783
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names DC-10
Calculated MW 48kDa
Dilution IHC-P (1-10 µg/ml), WB (1-2 µg/ml),
Additional Information
Gene ID 3875
Other Names Keratin, type I cytoskeletal 18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, CK-18, Keratin-18, K18, KRT18, CYK18
Reconstitution & Storage Stable for 36 months when stored at or below 0°C.
PrecautionsKRT18 / CK18 / Cytokeratin 18 Antibody (clone DC-10, Azide-free) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KRT18
Synonyms CYK18
Function Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
Cellular Location Nucleus matrix {ECO:0000250|UniProtKB:Q5BJY9}. Cytoplasm, perinuclear region. Nucleus, nucleolus. Cytoplasm {ECO:0000250|UniProtKB:Q5BJY9}
Tissue Location Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma.
Research Areas
Citations (0)
citation

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Background

Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

References

Oshima R.G.,et al.Differentiation 33:61-68(1986).
Kim J.W.,et al.Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Kulesh D.A.,et al.Mol. Cell. Biol. 8:1540-1550(1988).

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$ 467.50
Cat# ALS16044
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