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DDC / DOPA Decarboxylase Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, E |
|---|---|
| Primary Accession | P20711 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 54kDa |
| Dilution | IF (20 µg/ml), IHC-P (10 µg/ml), WB (1 µg/ml) |
| Gene ID | 1644 |
|---|---|
| Other Names | Aromatic-L-amino-acid decarboxylase, AADC, 4.1.1.28, DOPA decarboxylase, DDC, DDC, AADC |
| Target/Specificity | DDC antibody is human, mouse and rat reactive. |
| Reconstitution & Storage | Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
| Precautions | DDC / DOPA Decarboxylase Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DDC {ECO:0000303|PubMed:15532536, ECO:0000312|HGNC:HGNC:2719} |
|---|---|
| Function | Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine and L-5-hydroxytryptophan to serotonin. |
| Tissue Location | [Isoform 2]: High expression in kidney. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Catalyzes the decarboxylation of L-3,4- dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
References
Ichinose H.,et al.Biochem. Biophys. Res. Commun. 164:1024-1030(1989).
Scherer L.J.,et al.Genomics 13:469-471(1992).
Sumi-Ichinose C.,et al.Biochemistry 31:2229-2238(1992).
Vassilacopoulou D.S.,et al.Neurochem. Res. 29:1817-1823(2004).
Hillier L.W.,et al.Nature 424:157-164(2003).
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