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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Interleukin signaling   >   IL3RA / CD123 Antibody (aa200-305, clone 10B8E7)   

IL3RA / CD123 Antibody (aa200-305, clone 10B8E7)

Mouse Monoclonal Antibody

     
  • IHC - IL3RA / CD123 Antibody (aa200-305, clone 10B8E7) ALS15994
    Anti-IL3RA / CD123 antibody IHC staining of human kidney.
    detail
  • WB - IL3RA / CD123 Antibody (aa200-305, clone 10B8E7) ALS15994
    Western blot using IL3RA monoclonal antibody against HEK293 (1) and IL3RA (AA: 200-305)-hIgGFc...
    detail
  • IF - IL3RA / CD123 Antibody (aa200-305, clone 10B8E7) ALS15994
    Immunofluorescence of HeLa cells using IL3RA mouse monoclonal antibody (green).
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, ICC, E, FC
Primary Accession P26951
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 10B8E7
Calculated MW 43kDa
Dilution ELISA (1:10000), ICC (1:200-1:1000), IHC-P (10 µg/ml), WB (1:500-1:2000) ,
Additional Information
Gene ID 3563
Other Names Interleukin-3 receptor subunit alpha, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA, CD123, IL3RA, IL3R
Target/Specificity Human IL3RA / CD123
Format Ascitic fluid containing 0.03% sodium azide
Reconstitution & Storage Long term: -20°C; Short term: -20°C
PrecautionsIL3RA / CD123 Antibody (aa200-305, clone 10B8E7) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL3RA (HGNC:6012)
Synonyms IL3R
Function Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells (PubMed:10527461). Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein.
Volume Array
Research Areas
Citations (0)
citation

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Background

This is a receptor for interleukin-3.

References

Kitamura T.,et al.Cell 66:1165-1174(1991).
Kosugi H.,et al.Biochem. Biophys. Res. Commun. 208:360-367(1995).
Chen J.,et al.J. Biol. Chem. 284:5763-5773(2009).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ross M.T.,et al.Nature 434:325-337(2005).

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$ 467.50
Cat# ALS15994
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