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KRT5 / CK5 / Cytokeratin 5 Antibody (clone 2C2)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, ICC, E, FC |
|---|---|
| Primary Accession | P13647 |
| Reactivity | Human, Mouse, Monkey |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 2C2 |
| Calculated MW | 62kDa |
| Dilution | ELISA (1:10000), Flo (1:200-1:400), ICC (1:200-1:1000), IF (1:1000), IHC-P (10 µg/ml), WB (1:500-1:2000), |
| Gene ID | 3852 |
|---|---|
| Other Names | Keratin, type II cytoskeletal 5, 58 kDa cytokeratin, Cytokeratin-5, CK-5, Keratin-5, K5, Type-II keratin Kb5, KRT5 |
| Target/Specificity | Human Cytokeratin 5 / Keratin 5 |
| Reconstitution & Storage | Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles. |
| Precautions | KRT5 / CK5 / Cytokeratin 5 Antibody (clone 2C2) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KRT5 |
|---|---|
| Function | Required for the formation of keratin intermediate filaments in the basal epidermis and maintenance of the skin barrier in response to mechanical stress (By similarity). Regulates the recruitment of Langerhans cells to the epidermis, potentially by modulation of the abundance of macrophage chemotactic cytokines, macrophage inflammatory cytokines and CTNND1 localization in keratinocytes (By similarity). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Expressed in corneal epithelium (at protein level) (PubMed:26758872). Expressed in keratinocytes (at protein level) (PubMed:20128788, PubMed:31302245). |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Eckert R.L.,et al.DNA 7:337-345(1988).
Lersch R.,et al.Mol. Cell. Biol. 9:3685-3697(1989).
Whittock N.V.,et al.Biochem. Biophys. Res. Commun. 274:149-152(2000).
Lersch R.,et al.Mol. Cell. Biol. 8:486-493(1988).
Xu Z.,et al.Clin. Exp. Dermatol. 29:74-76(2004).
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