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AGR2 Antibody (aa50-100, clone IMG10E2)

Mouse Monoclonal Antibody

     
  • WB - AGR2 Antibody (aa50-100, clone IMG10E2) ALS15546
    Western blot of AGR2 in A) human stomach tissue lysate in the absence of immunizing peptide, B)...
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  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession O95994
Reactivity Human, Mouse, Horse, Bovine, Dog
Host Mouse
Clonality Monoclonal
Clone Names IMG10E2
Calculated MW 20kDa
Dilution IHC-P (10 µg/ml), WB (4-6 µg/ml),
Additional Information
Gene ID 10551
Other Names Anterior gradient protein 2 homolog, AG-2, hAG-2, HPC8, Secreted cement gland protein XAG-2 homolog, AGR2, AG2
Target/Specificity Human AGR2
Reconstitution & Storage Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.
PrecautionsAGR2 Antibody (aa50-100, clone IMG10E2) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AGR2
Synonyms AG2
Function Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. Promotes cell adhesion (PubMed:23274113).
Cellular Location Secreted. Endoplasmic reticulum {ECO:0000250|UniProtKB:O88312}
Tissue Location Expressed strongly in trachea, lung, stomach, colon, prostate and small intestine. Expressed weakly in pituitary gland, salivary gland, mammary gland, bladder, appendix, ovary, fetal lung, uterus, pancreas, kidney, fetal kidney, testis, placenta, thyroid gland and in estrogen receptor (ER)-positive breast cancer cell lines
Research Areas
Citations (0)
citation

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Background

Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth.

References

Thompson D.A.,et al.Biochem. Biophys. Res. Commun. 251:111-116(1998).
Zhang J.S.,et al.Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
Fan Y.X.,et al.Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.

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$ 467.50
Cat# ALS15546
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