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Nestin Antibody (clone 10C2)

Mouse Monoclonal Antibody

     
  • WB - Nestin Antibody (clone 10C2) ALS15204
    U251 cell lysates prepared under non-reducing (lane 1) or reducing (lane 2) conditions were...
    detail
  • IHC - Nestin Antibody (clone 10C2) ALS15204
    Anti-Nestin antibody IHC of human heart.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IHC-F
Primary Accession P48681
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 10C2
Calculated MW 177kDa
Dilution IHC-P (20 µg/ml)
Additional Information
Gene ID 10763
Other Names Nestin, NES
Reconstitution & Storage Store at 4°C, avoid repeated freeze thaw cycles.
PrecautionsNestin Antibody (clone 10C2) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NES
Function Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen- stimulated proliferation of neural progenitor cells (By similarity).
Tissue Location CNS stem cells.
Research Areas
Citations (0)
citation

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Background

Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity).

References

Dahlstrand J.,et al.J. Cell Sci. 103:589-597(1992).
Gregory S.G.,et al.Nature 441:315-321(2006).
Yaworsky P.J.,et al.Dev. Biol. 205:309-321(1999).
Ohira M.,et al.Cancer Lett. 197:63-68(2003).
Olsen J.V.,et al.Cell 127:635-648(2006).

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$ 467.50
Cat# ALS15204
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