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KRT1 / CK1 / Cytokeratin 1 Antibody (Internal)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P04264 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 66kDa |
| Dilution | ELISA (1:10000-1:80000), IHC-P (1:100), WB (1:200-1:1000) |
| Gene ID | 3848 |
|---|---|
| Other Names | Keratin, type II cytoskeletal 1, 67 kDa cytokeratin, Cytokeratin-1, CK-1, Hair alpha protein, Keratin-1, K1, Type-II keratin Kb1, KRT1, KRTA |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
| Precautions | KRT1 / CK1 / Cytokeratin 1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KRT1 |
|---|---|
| Synonyms | KRTA |
| Function | May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK. |
| Cellular Location | Cell membrane. Cytoplasm |
| Tissue Location | The source of this protein is neonatal foreskin. The 67-kDa type II keratins are expressed in terminally differentiating epidermis |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein kinase C (RACK1/GNB2L1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK.
References
Johnson L.D.,et al.Proc. Natl. Acad. Sci. U.S.A. 82:1896-1900(1985).
Whittock N.V.,et al.Biochem. Biophys. Res. Commun. 274:149-152(2000).
Hatsell S.J.,et al.J. Invest. Dermatol. 116:606-609(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
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