COX17 Antibody (aa1-50)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q14061 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 7kDa |
Dilution | ELISA (1:5000), IHC-P (10 µg/ml), WB (1:500-1:1000) |
Gene ID | 10063 |
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Other Names | Cytochrome c oxidase copper chaperone, COX17 |
Target/Specificity | COX17 Antibody detects endogenous levels of total COX17 protein. |
Reconstitution & Storage | Store at -20°C for up to one year. |
Precautions | COX17 Antibody (aa1-50) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | COX17 |
---|---|
Function | Copper metallochaperone essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Binds two copper ions and delivers them to the metallochaperone SCO1 which transports the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2). |
Cellular Location | Mitochondrion intermembrane space. Cytoplasm |
Tissue Location | Ubiquitous.. |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX (By similarity).
References
Amaravadi R.,et al.Hum. Genet. 99:329-333(1997).
Punter F.A.,et al.Hum. Genet. 107:69-74(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
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