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TUBB / Beta Tubulin Antibody (aa401-450)

Rabbit Polyclonal Antibody

     
  • WB - TUBB / Beta Tubulin Antibody (aa401-450) ALS15085
    Western blot of extracts from mouse brain/rat brain cells, using Tubulin beta Antibody.
    detail
  • IHC - TUBB / Beta Tubulin Antibody (aa401-450) ALS15085
    Anti-TUBB3 / Beta III Tubulin antibody IHC of human brain, cerebellum.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P07437
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 50kDa
Dilution ELISA (1:5000), IHC-P (10 µg/ml), WB (1:500-1:1000)
Additional Information
Gene ID 203068
Other Names Tubulin beta chain, Tubulin beta-5 chain, TUBB, TUBB5
Target/Specificity Tubulin beta Antibody detects endogenous levels of total Tubulin beta protein.
Reconstitution & Storage Store at -20°C for up to one year.
PrecautionsTUBB / Beta Tubulin Antibody (aa401-450) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TUBB
Synonyms TUBB5
Function Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
Cellular Location Cytoplasm, cytoskeleton
Tissue Location Ubiquitously expressed with highest levels in spleen, thymus and immature brain.
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

References

Lee M.G.-S.,et al.Cell 33:477-487(1983).
Hall J.L.,et al.Mol. Cell. Biol. 3:854-862(1983).
Crabtree D.V.,et al.Bioorg. Med. Chem. 9:1967-1976(2001).
Yu W.,et al.Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases.
Shiina S.,et al.Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.

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$ 467.50
Cat# ALS15085
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