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IKZF3 / AIOLOS Antibody (aa350-400)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | Q9UKT9 |
| Reactivity | Human, Monkey |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 58kDa |
| Dilution | IHC-P (10 µg/ml), WB (0.25-1 µg/ml), |
| Gene ID | 22806 |
|---|---|
| Other Names | Zinc finger protein Aiolos, Ikaros family zinc finger protein 3, IKZF3, ZNFN1A3 |
| Target/Specificity | Human IKZF3 |
| Reconstitution & Storage | Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C. |
| Precautions | IKZF3 / AIOLOS Antibody (aa350-400) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | IKZF3 |
|---|---|
| Synonyms | ZNFN1A3 |
| Function | Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner. |
| Cellular Location | Nucleus. Cytoplasm [Isoform 3]: Nucleus [Isoform 14]: Nucleus. Cytoplasm |
| Tissue Location | Expressed most strongly in peripheral blood leukocytes, the spleen, and the thymus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2- dependent manner.
References
Hosokawa Y.,et al.Genomics 61:326-329(1999).
Liippo J.P.,et al.Eur. J. Immunol. 31:3469-3474(2001).
Caballero R.,et al.J. Cell Sci. 120:2619-2630(2007).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
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